The histone methyltransferase MMSET, which is highly correlated with EZH2 in many other solid cancers (Asangani et al., manuscript in review), also demonstrated increased expression in melanoma cell lines relative to primary melanocytes (Figure 5A), and was correlated with EZH2 expression in melanoma cells (Supplementary Figure 6B). This evidence concerns the gene EZH2 and melanoma.