HIRI levels correlated significantly with ALT in all subjects with a metabolic diagnosis: MetS (r = 0.22, p = 0.003), IFG (r = 0.33, p < 0.001), IGT (r = 0.37, p < 0.001), and T2DM (r = 0.72, p < 0.001). The gene discussed is GPT; the disease is type 2 diabetes mellitus.