Like many other pro-inflammatory cytokines, resistin stimulates intracellular signalling through NF-κB activation, which in turn promotes the synthesis of other pro-inflammatory cytokines, including MCP-1, vascular cell adhesion molecule-1 (VCAM-1), as well as intercellular adhesion molecule-1 (ICAM-1), which are involved in chemotactic pathways directing leukocyte recruitment to sites of infection [30,31]. This evidence concerns the gene NFKB1 and infection.