Non-inhibitory serpins in animals act in diverse roles such as hormone carriage, as performed by corticosteroid binding globulin (CBG or SERPINA6)) and thyroxine binding globulin (TBG or SERPINA7), tumour suppression (maspin or SERPINB5), chaperone activity (HSP47 or SERPINH1) and protein storage (ovalbumin) [57]. This evidence concerns the gene SERPINH1 and neoplasm.