Laboratory investigations showed a total white cell count of 12,500/mm3 with 2% eosinophils, 14.9 g/dL hemoglobin, 245,000 platelets/mm3 and 0.17 mg/dL CRP with no eosinophilia in the stool, and serum allergy investigations revealed no remarkable elevation of non-specific IgE (1 IU/mL) and cow’s milk-spcific IgE (<0.34 IU/mL). The gene discussed is IGHE; the disease is allergic disease.