HSPA5 and hepatocellular carcinoma: In agreement with our data, GRP78 silencing increased cell migration in both HepJ5 and Mahlavu cells and overexpressed GRP78 suppressed the migratory ability of skHep1 cells and this effect on GRP78-mediated cell migration was attributed to an increased vimentin expression in hepatocellular carcinoma cells [16,17].