EFEMP2 and aortic aneurysm: Compound heterozygous mutations ((c.835C > T (p.R279C) /c.1070_1073dupCCGC) in FBLN4 causing a severe phenotype including cutislaxa and aortic aneurysm and tortuosity resulting in death at 27 days age wasreported by Dasouki et al. [29].