For example, RAR-L3 (8p21.2) and RAR-L5 (17p12), where PPP2R2A and MAP2K4 are located, respectively, and RAR-G13 (17q12), where ERBB2 is located, were consistently detected in a recent large-scale breast cancer genetic subgroup study [14]. This evidence concerns the gene PPP2R2A and breast cancer.