CST3 and cervical squamous intraepithelial neoplasia: In individuals with CIN median serum creatinine levels rose from 140 μmol/L (IQR 103–164) at baseline to 170 μmol/L (110–202) and 202 μmol/L (125–266) at 24 and 48 hours, respectively (p = 0.02 for baseline vs. 48 hours), whereas cystatin C levels had already increased significantly from 2.06 mg/L (IQR 1.38-2.48) at baseline to 2.65 mg/L (1.77-3.10) at 24 hours (p = 0.038).