The cardiovascular disease associated SNPs found in this individual include those in LRP8 (R952Q; rs5174/OMIM_ID # 602600.0001;[66]) and MMP9 (Q166R; rs17576;[67]) both of which increase risk for myocardial infarction, ROS1 (S2229C; rs619203;[68]) variation associated with increased coronary heart disease, AKAP10 SNP (I646V; OMIM_ID # 604694.0001;[69]) associated with cardiac conductivity defect susceptibility and ADRB3 variant (W64R; rs4994;[70]) implicated in higher risk of cardiac events. This evidence concerns the gene ROS1 and cardiovascular disorder.