GYPA and malaria: Basing on the knowledge base that--merozoites of the two most prevalent Plasmodium speciesfalciparum and vivax respectively, by using- the Duffy Antigen Receptor for Chemokines (DARC), and Sialic Acid (SLC4A1) residues of the O-linked glycans of Glycophorin A specifically target and invade red blood cells (RBCs), we hypothesized that artificial aberration of either host-pathway by target mutagenesis of the respective RBC –receptors, may abolish or reduce susceptibility of the host to malaria[14-23].