Several molecular signals, such as signal transducer and activator of transcription-3 (STAT-3), nuclear factor-êB, Akt, mitogen-activated protein kinases, cyclooxygenase-2, lipoxygenase, inducible nitric-oxide synthase, tumor necrosis factor and others, have also been shown to be involved in tumor progression and angiogenesis [7]–[9]. Here, STAT3 is linked to neoplasm.