Importantly, this analysis highlighted new potential dystrophin-associated proteins that were specific to cardiac DYS-IPs and involved proteins with known associations to cardiac disease in humans: Cavin-1 (PTRF) [16], [17], Ahnak1 (desmoyokin) [18], Cypher (LDB3, ZASP) [19], [20], [21], and Crystallin alpha B (CRYAB) [22], [23]. The gene discussed is CRYAB; the disease is heart disorder.