For example, gene expression of Stk32c, an upstream activator of AMPK as well as Prkag1, the protein kinase AMP-activated gamma 1 non-catalytic subunit for AMPK, were increased in HF Acads−/− compared to HF Acads+/+ but were decreased in HF Acads+/+ vs. LF Acads+/+. The gene discussed is STK32C; the disease is hydrops fetalis.