Despite the positive correlation between SATB1 and SATB2 expression in CRC, it is evident that the expression pattern of SATB1 in normal mucosa and CRC differs from SATB2, which is abundantly expressed in a tissue-specific manner in the mucosa of the lower gastrointestinal tract and in the vast majority of CRC [3,4]. Here, SATB2 is linked to colorectal carcinoma.