The expression of EGFRvIII, EGFR, PDGFR, MET, PTEN, and other GBM-related oncogenic and tumor suppressive proteins was also noted in other models of high grade glioma (U87, U87vIII, U87-PTEN) (Al-Nedawi et al., 2010; Lee et al., 2011b). Here, PTEN is linked to malignant glioma.