PDGFRB and glioblastoma: Rapid progress in molecular characterization of adult and pediatric GBM has recently been extended to RTKs (PDGFR, MET) (Paugh et al., 2011), mutant forms of histone H3.3 and chromatin remodeling genes (Schwartzentruber et al., 2012), as well as several other events involving genetic and epigenetic alterations (Parsons et al., 2008; Lavon et al., 2010).