The patients with p73-over-expressing tumours tended to have a higher local recurrence after RT compared to non-RT cases.12 MAC30 mRNA is expressed in the foetal liver, but not in the adult liver, suggesting a possible role in growth and differentiation of liver.27,28 The expression of MAC30 is stronger in breast, stomach and colorectal cancers than the corresponding normal tissues14,29,30, indicating that MAC30 may act as an oncogene in the cancers and might play a role in tumour development and aggressiveness. Here, TMEM97 is linked to neoplasm.