NFKB1 and neoplasm: The function of NF-κB is inhibited by binding to NF-κB inhibitory proteins, and imbalance of NF-κB and its inhibitors has been associated with development of tumours and other diseases.1–3 Five members of the NF-κB family have been found in human cells, RelA (p65), p105/p50, p100/p52, RelB and c-Rel.