GSTM1 and small cell lung carcinoma: This is in accordance with performance status patient’s selection in prospective studies.17 The majority of patients were heavy smokers as was expected in population of patients with SCLC.18 Heavy smokers have comorbidities and therefore usually lower performance status, making them less likely candidates for radical treatment and also for PCI.19 Bremnes et al. reported gender, extent of disease, PS, Hb levels and LDH to be independent prognostic factors.20 In our analyses only age < 65 years and PS were independent factors of survival in multivariate analysis.