Various studies revealed deletions of the RB1 gene region in testicular cancer.5 For example, Peng et al. 24 used short variable number of tandem repeats in RB1 introns 16 and 20, and found LOH in 5% of seminomas and 28% of nonseminomas analyzed within 93% of informative TGCT cases. This evidence concerns the gene RB1 and seminoma.