A significantly higher CFH Y402H risk allele frequency was found in the CD cohort when compared with the control cohort (p<0.001; OR: 2.88; 95% CI: 2.23–3.73), and when compared to the “non-CD” AMD cohort (p=0.022; OR: 1.35; 95% CI: 1.04–1.74). Here, CFH is linked to age-related macular degeneration.