Increased EAAT-3 immunoreactivity (IR) in granule cells of DG during the acute epileptic phase (24 h) was observed in the animal model of status epilepticus (SE) induced by electrical stimulation [29], and increases in EAAT-3 and GAT-1 IR have been described in granular and pyramidal cells of hippocampal sections from TLE patients [13,14]. The gene discussed is SLC1A1; the disease is status epilepticus.