High expression levels of Hsp90-beta and annexin A1 in lung cancer cases without lymph node metastasis were both 26.8%, which is lower than what was noted in lung cancer cases with lymph node metastases as follows: N1, 85% and 60%; N2, 81.8% and 81.82%; and N3, 100% and 100%, respectively (p < 0.0005) (Figures 2C and D). This evidence concerns the gene ANXA1 and lung cancer.