NR1H4 and inflammatory bowel disease: Upon statistical analysis of the allele (Table3) and genotype (Table2) frequencies, we observed that the NR1H4 variant rs3863377 is significantly less frequent in IBD cases than in non-IBD controls (allele frequencies: P = 0.004; wild-type vs. SNP carrier genotype frequencies: P = 0.008) even when considering an Bonferroni-corrected significance level of P<0.01.