There were no differences in Bcl-2 mRNA expression in the CH tissues in relation to the type of viral infection involved (HBV-HCV), but statistically significant differences were found between PHCC HCV (7.65 ± 3.8) and both CH HCV-infected tissues (3.79 ± 1.1; P = 0.012) and Contr (4.163.79 ± 1.1; P = 0.04). The gene discussed is BCL2; the disease is cyclic hematopoiesis.