MAPT and ischemia: The group of Gozes in the paper: “Tau and caspase 3 as targets for neuroprotection” shows clearly that in an in vitro model for ischemia, in primary neuronal cultures subjected to oxygen-glucose deprivation that causes an increase in the levels of active caspase-3 and hyperphosphorylated tau, both processes are prevented by either the NAP peptide or caspase-inhibitor treatment.