The EML4 gene is nearly always the partner gene for ALK fusions in lung cancer, although more recent studies have identified a small subset (<1%) of fusions between kinesin family member 5b and ALK (KIF5B-ALK) [100, 101], and others between TRK-fused gene (TFG) and kinesin light chain1 (KLC-1) to an even smaller percentage [102, 103]. The gene discussed is EML4; the disease is lung cancer.