PSIP1 and HIV infectious disease: In spite of the identification of the interaction between HIV-1 IN and LEDGF/p75, definition of the IBD in LEDGF/p75, a clear phenotype of IN relocalization after LEDGF/p75 knockdown, and the role of LEDGF/p75 in HIV infection remained disputed for some years, especially after one publication dismissing such role [78].