The delay observed to produce IFN-γ and to activate Vγ9Vδ2 T cells did not allow studying DC maturation with a 72 h infection protocol and in vitro we could not keep infected cells in culture longer than 72 h p.i. Nevertheless, as HMB-PP-stimulated Vγ9Vδ2 T cells are activated rapidly (24 h) after contact with DCs (Fig. 6, white and white striped bars), we could use this activation protocol to study the effects of a delayed addition of Vγ9Vδ2 T cells on DC maturation and activity. The gene discussed is IFNG; the disease is infection.