In a multivariate analysis using Cox model, we noted that XB130, CEA, chemotherapy and ascites (all p<0.01) were independent factors to predict HR for death in patients at stage IV, while XB130 (p = 0.044) and stage (p<0.000) were independent factors to predict HR for reoccurrence after radical resection of GC in patients at stage I–III (Table 2). This evidence concerns the gene CEACAM5 and gastric cancer.