S-nitrosylation of Parkin, protein disulfide isomerase (PDI), peroxiredoxin 2 (Prx2), X-linked inhibitor of apoptosis (XIAP), and Drp1 has been implicated in stress-induced neuronal death [59, 157–159] and has been also observed in brains from patients with neurological disorders. Here, P4HB is linked to nervous system disorder.