ADH5 and asthma: It is desirable that, in the next future, transgenic mouse models of impaired denitrosylation, alongside with synthetic inhibitors of denitrosylating enzymes, namely, GSNOR, which have been recently designed [209–211] and yielded for the treatment of asthma, will be used to dissect how denitrosylation reactions, mainly those occurring within the mitochondria, are involved in the onset of several diseases.