In particular, the following SNPs in the IGFBPs (rs10228265, rs4988515, rs2270628, rs2854746, and rs2854744), in IGF-I (rs11111285, rs1996656 and rs1019731), and in IGF-II (rs4320932, rs4244809, rs680, rs1003483, and rs7924316) have been associated with increased ovarian cancer risk [119, 120]. This evidence concerns the gene IGF2 and ovarian cancer.