Also by IHC and TMA, Mcm-2 has been proved to be a proliferative sensitive marker for SGTs and PLUNC proteins have been suggested to be useful diagnostic tools for mucoepidermoid carcinoma, whereas geminin has been strongly associated with reduced overall and relapse-free survival rates in patients affected by salivary gland carcinomas (1,19,20). The gene discussed is BPIFA1; the disease is mucoepidermoid carcinoma.