WNT4 and endometriosis: However, there was evidence for replication of rs7521902 on 1p36, close to WNT4 gene, with the strongest signal for stage B endometriosis (P = 7.5 × 10−6, OR = 1.25, 95 % CI 1.13–1.38); meta-analysis of the evidence from “any” endometriosis (as severity of disease was not assessed in the Japanese GWAS) combining the three GWAS datasets resulted in a genome-wide significant P value of 4.2 × 10−8 (OR = 1.19, 95 % CI 1.12–1.27).