Although the study of such tumor by CGH showed a simple genomic profile with only a few amplifications which is suggestive of DL [9], the presence of MDM2 gene amplification per se cannot be equated with the presence of a DL, since MDM2 gene amplification by FISH can be identified in up to 40% of pleomorphic sarcomas [10]. This evidence concerns the gene MDM2 and neoplasm.