Older individuals have been found to have glomerulopathy, that manifests as microalbuminuria (MiA, defined as urine albumin of 30–300 mg/g urine creatinine), macroalbuminuria (MaA, defined as urine albumin >300 mg/g urine creatinine), or end-stage renal disease (ESRD) [544, 545, 548, 549]. The gene discussed is ALB; the disease is lipoprotein glomerulopathy.