TGFB1 and chronic pancreatitis: Although the decrease of TGF-β and PDGF-β mRNA expression in caerulein induced chronic pancreatitis mice fed with sulindac diet did not reach statistical significance, the protein expression of TGF-β and PDGF-β were upregulated in chronic pancreatitis mice and sulindac treatment significantly decreased TGF-β and PDGF-β expression at the protein level.