The isolated compound (VAD) and the crude methanolic extract (MEPG) had been evaluated for antidiabetic activity; aldose reductase inhibition assay, PTP1B assay, and α-amylase inhibition assays were used for in vitro evaluation, and alloxan-induced diabetes in rats was used as an in vivo model. This evidence concerns the gene PTPN1 and diabetes mellitus.