The well-known ABC transporters, P-glycoprotein (Pgp)/MDR1/ABCB1, multidrug resistance protein (MRP)1/ABCC1, and breast cancer-resistance protein (BCRP)/MXR/ABCG2, are overexpressed in a variety of different human cancers and transport a range of chemotherapeutic drugs [4]. The gene discussed is ABCG2; the disease is cancer.