DNMT3B and neoplasm: In addition, DNMT3B expression was higher in patients with resection margins free of tumor cells (R0: median = 0.65, Q1–Q3 = 0.26–1.16), than in those with evidence of tumor infiltration on resected margins (R1: median = 0.20, Q1–Q3 = 0.12–0.42), P = 0.04 (Figure 3).