Analysis of the association among PPARγ, DNMT1, and DNMT3B mRNA levels showed that PPARγ expression levels were positively correlated with DNMT1 expression levels in PC patients (r = 0.48, P = 0.008), but not with DNMT3B expression levels (r = −0.20, P = 0.30). This evidence concerns the gene PPARG and pachyonychia congenita.