Neural-associated CXCR7 staining score was significantly enhanced in differentiated tumors, such as ganglio-neuroblastomas (GGNBs) (median score of 0.93±0.65, p<0.05) and ganglioneuromas (GGNs) (median score of 1.62±0.64, p<0.01), when compared to undifferentiated NBs (UnNBs) (median score of 0.57±0.37). Here, ACKR3 is linked to Nijmegen breakage syndrome.