The exogenous expression of CD157 proved to be sufficient to convert immobile OVCAR-3 epithelial cells into mesenchymal-like cells characterized by weak contacts between neighboring cells, increased motility, invasiveness, tumorigenicity, and improved resistance to anoikis, all properties known to be fundamental prerequisites for the progression of primary tumors to metastatic disease [38]. The gene discussed is BST1; the disease is metastatic neoplasm.