The observed CD157-induced effects were not limited to a single ovarian cancer cell line, indeed, transient transfection of CD157 in CD157-negative TOV-21G epithelial cells (Figure S1A) was accompanied by decreased expression of E-cadherin and slightly increased expression of N-cadherin proteins (Figure S1B), and caused accumulation of β-catenin in the nuclear extracts (Figure S1C). The gene discussed is CDH1; the disease is ovarian cancer.