This apparent inconsistency with what is thought to be the rule in ovarian cancer, suggests that i) small aggregates of cells provide more favorable conditions for anchorage-independent tumor cell survival than large aggregates, and that ii) tumor cells expressing high CD157 likely develop strategies relying on specific pro-survival signals, allowing both individual cells and small aggregates that have detached from the tumor to escape anoikis and to grow under anchorage-independent conditions. Here, BST1 is linked to neoplasm.