The sensitivity and specificity of the plasma hTERT mRNA assay with respect to detecting PCa were 91% and 85%, respectively (best cut-off value 0.45), (best cut-off value 0.45, with an AUC ROC curve of 0.932±0.027), whereas the PSA assay showed a sensitivity of 83% and a specificity of 47% (best cut-off value 7.2 ng/ml, (best cut-off value 7.2 ng/ml, with an AUC ROC of 0.651±0.054 (Figure 3). The gene discussed is KLK3; the disease is posterior cortical atrophy.