KLK3 and neoplasm: The results confirm and extend those of a previous report, as they indicate that plasma hTERT mRNA is a non-invasive tumor marker which can be used for PCa diagnosis, showing higher sensitivity (85% vs. 83%), specificity (90% vs. 47%), PPV (83% vs. 56%), NPV (92% vs. 77%) and LR ratios than the PSA assay.