Employing a comprehensive list of transcript-specific primer/probe sets (Table 1) for q-RT-PCR, we measured gene expression of (1) general makers of MSNs, (2) direct pathway MSN markers, (3) indirect pathway MSN markers, and (4) interneuron markers in PGC-1α +/+, +/−, and −/− mice and R6/2 and WT mice at four and twelve weeks of age, time points that are presymptomatic and end-stage, respectively, for the R6/2 model of HD. The gene discussed is PPARGC1A; the disease is Huntington disease.