STK11 and Peutz-Jeghers syndrome: In order to investigate whether deletion of LKB1 from reproductive tract and gonadal stromal cells leads to the gynecological abnormalities observed in PJS patients, we generated mice with conditional deletion of LKB1 in the stromal cells of the female reproductive tract using Müllerian inhibiting substance receptor 2-driven Cre (Misr2-Cre) [16].