This time-dependent difference in Ccr1-mediated leukocyte accumulation in the kidney was exclusively accounted for by Ly6cintLy6G+CD11b+ neutrophils, which accumulated in a Ccr1-independent manner until day 6 post-infection, but thereafter were ∼60% decreased in Ccr1−/− kidneys (Figure 4B, 4C and 4D; P≤0.01). This evidence concerns the gene CCR1 and infection.