Of the cytokines induced (Figure 1B), IL-1α, IL-1β, IL-6, IL-10, IL-17A, IL-18, IFN-γ, and TNF-α have been previously shown to play an important role in the pathogenesis of invasive candidiasis in vivo[13]–[21]. This evidence concerns the gene IFNG and Candidiasis, Invasive.