The ROC AUC for the prediction of a Catot/Caion ratio ≥2.5 was 0.71 for aspartate aminotransferase, 0.49 for alanine aminotransferase, 0.67 for bilirubin, 0.73 for cholinesterase, 0.69 for the Child-Pugh score, 0.84 for the Model of End-stage Liver Disease score, and 0.54 for the plasma disappearance rate for indocyanine green. This evidence concerns the gene BCHE and End Stage Liver Disease.