ADAMTS1 and Anxiety: Because several lines of evidence indicate the involvement of GABAA receptors in the function of the hippocampus associated with not only anxiety and fear but also memory and learning[18,19], the present study suggests that the transcriptional activation of Btg2 and Adamts1 followed by the anxiogenic drug-induced reduction in the transmission of the GABAA receptors in the adult hippocampus may be involved in changes of the neural functions in the emotional states and memory of the experience.