In vivo, compared with medium treated group, TSG-6-siRNA MSCs-CM had no significant effect on the size, severity (Figure 8B1) (mean score: 3.6 vs. 2.5, p >0.05, n  = 6, respectively) or the histological changes (Figure 8B2, Figure 8B3 and Figure S5) (mean score: 3.0 vs. 2.4, p > 0.05, n  = 6, respectively) of peritoneal adhesions 14 days after scraping. Here, TNFAIP6 is linked to peritoneal well differentiated papillary mesothelioma.