TLR3 and toxic epidermal necrolysis: In the present study we examined the multiplicative interaction(s) between HLA-A*0206 and 7 TLR3 SNPs (rs3775296 (uSNP), rs5743312 (iSNP), rs6822014 (gSNP), rs3775290 (sSNP), rs7668666 (iSNP), rs11732384 (iSNP), and rs4861699 (gSNP)) associated with the SJS/TEN patients [12], [17] as the onset of SJS/TEN was associated not only with the administration of drugs but also with putative viral syndromes [10], [11], [12], [17].