We focused on the production of IFNβ as it appears to be the primary type I IFN family member that is induced after infection with Lm. We infected C57BL/6 mice with Lm or E. coli (106 CFU) and extracted total RNA at different time points from whole spleens and from CD11c+ cells purified by magnetic bead cell sorting. Here, IFNB1 is linked to infection.